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【2025 原著論文, Research papers】

R. Mizutori, M. Sugiura, H. Kandori*
"Protonation states of highly conserved carboxylic acids in NeoR"
Biophysics and Physicobiology. 2025, 22, e220032
10.2142/biophysico.bppb-v22.0032

Y. Mizuno, S. Arai, K. Katayama*,  H. Kandori*
"Schiff base deprotonation and structural changes in a mouse UV-sensitive cone visual pigment revealed by FTIR spectroscopy at 77 K"
Biophysics and Physicobiology. 2025, 22, e220030
10.2142/biophysico.bppb-v22.0030

M. Aoyama, K. Katayama, H. Kandori*
"FTIR Spectroscopy of a Viral Rhodopsin, OLPVR2"
The Journal of Physical Chemistry B
10.1021/acs.jpcb.5c06817

M. Aoyama, K. Katayama, H. Kandori*
"FTIR study of the wild-type and mutant proteins of a viral rhodopsin, OLPVR1"
Biophysics and Physicobiology. 2025, 22, e220029
10.2142/biophysico.bppb-v22.0029

C. Suno-Ikeda, R. Nishikawa, R. Suzuki, S. Yokoi, S. Iwata, T. Takai, T. Ogura, M. Hirose, A. Tokuda, R. Katamoto, A. Inoue, E. Asai, R. Kise,
 Y. Sugita, T. Kato, H. Nagase, A. Mitsutake, T. Saitoh, K. Katayama, A. Inoue, H. Kandori, T. Kobayashi*, R. Suno*
"Structural and Dynamic Insights into the Biased Signaling Mechanism of the Human Kappa Opioid Receptor"
Nat. Commun.16, 9392, 2025
10.1038/s41467-025-64882-1

Y. Mizuno, V. Panneels, Y. Furutani*, G.F.X. Schertler, H. Kandori, K. Katayama*
"Light-induced FTIR spectroscopy of visual rhodopsin microcrystals grown in lipidic cubic phase"
J. Mol. Biol. 437,169487(2025)
10.1016/j.jmb.2025.169487

R. Mizutori, K. Katayama, M. Konno, K. Inoue, O. Béjà, H. Kandori*
"Molecular properties of a viral heliorhodopsin, V2HeR2"
Biophysics and Physicobiology. 2025, 22, e220024 
10.2142/biophysico.bppb-v22.0024

Y. Ito, T. Nishikino, H. Kandori, Y. Furutani*
"The role of retinal chromophore photoisomerization in enhanced inward proton-pumping activity of xenorhodopsin from Nanosalina"
Biochim. Biophys. Acta Bioenergetics 1866 (3), 149556, 2025
10.1016/j.bbabio.2025.149556

Y. Wang, K. Natsume, T. Tanaka, S. Hososhima, R. Tashiro, F. K. Sano, H. Akasaka, S. P. Tsunoda, W. Shihoya*, H. Kandori*, O. Nureki*
"Cryo-EM structure of a blue-shifted channelrhodopsin from Klebsormidium nitens"
Nat. Commun. 16, 5297, 2025
10.1038/s41467-025-59299-9

Y. Mizuno, K. Katayama*, H. Imai, H. Kandori*
"Deprotonation of retinal Schiff base and structural  dynamics in the early photoreaction of primate blue  cone visual pigment"
Biophys J. 124 (12), 2070-2081, 2025
10.1016/j.bpj.2025.05.004

D. Tzlil, M.d.C. Marín, Y. Matsuzaki, P. Nag, S. Itakura, Y. Mizuno, S. Murakoshi, T. Tanaka, S. Larom, M. Konno, R. Abe-Yoshizumi
A. Molina-Márquez,D. Bárcenas-Pérez, J. Cheel, M. Koblížek, R. León, K. Katayama, H. Kandori, I. Schapiro, W. Shihoya*, O. Nureki*, K. Inoue*,
A. Rozenberg*,A. Chazan*, O. Béjà*
"Structural insights into light harvesting by antenna-containing rhodopsins in marine Asgard archaea"
Nat. Microbiol. 10 (6), 1484-1500, 2025
10.1038/s41564-025-02016-5

S. Onoe, T. Nishikino, M. Kinoshita, N. Takekawa, T. Minamino, K. Imada, K. Namba, J. Kishikawa*, T. Kato*
"Cryo-EM Structure of Flagellar motor complex from Paeni-bacillus sp. TCA20"
Biomolecules, 15 (3), 435, 2025
10.3390/biom15030435

Y. Sugiura, T Ikuta, Y. Sumii, H. Tsujimoto,K. Suzuki, R. Suno, P. N. A. B. M. Ariff, S. Iwata, N. Shibata, A. Inoue, T. Kobayashi, H. Kandori, K. Katayama
"Discovering key activation hotspots in the M2 muscarinic receptor"
J. am. Chem. Soc. in press (2025)
10.1021/jacs.4c14385

T. Nishikino*, A. Hatano, S. Kojima, M. Homma
"Regulatory Role of a Hydrophobic Core in the FliG C-Terminal Domain in the Rotary Direction of a Flagellar Motor"
Biomolecules, 15 (2), 212, 2025
10.3390/biom15020212

T. Nishikino*, N. Takekawa, J. Kishikawa, M. Hirose, S. Kojima, M. Homma , T. Kato, K. Imada*
"Structural insight into sodium ion pathway in the bacterial flagellar stator from marine Vibrio"
Proc Natl Acad Sci U S A. 122 (1), e2415713122,2025
10.1073/pnas.2415713122

T. Urui, M. Mizuno,R. Abe-Yoshizumi, H. Kandori,  Y. Mizutani*
"Structural Evolution of Retinal Chromophore in Early Intermediates of Inward and Outward Proton-Pumping Rhodopsins"
J. Phys. Chem. B in press (2025)
10.1021/acs.jpcb.4c04793